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1
Effects of baicalein and wogonin on drug-metabolizing enzymes in C57BL/6J mice.
PubMed Open HTML    
Ueng YF Chen CF  » 
Life Sci (2000) Show Abstract »
Hepatic and renal UGT activities toward p-nitrophenol were suppressed by baicalein- and wogonin-treatments.
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2 Full-text article
Effects of flavonoids on sphingolipid turnover in the toxin-damaged liver and liver cells
BioMed Central Open HTML Open PDF     PubMed Open HTML    
Babenko NA, Shakhova EG
Lipids Health Dis (2008) Show Abstract »
The data obtained have demonstrated that flavonoids affect sphingolipid metabolism in the CCl4- and ethanol-damaged liver and liver cells.
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3
Resveratrol attenuates oxidative stress and histological alterations induced by liver ischemia/reperfusion in rats
PubMed Central Open HTML Open PDF     PubMed Open HTML    
Gedik E Buyukbayram H  » 
World J Gastroenterol (2008) Show Abstract »
In group 4, histopathological changes were significantly attenuated in resveratrol-treated livers.
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4
Resveratrol, a red wine polyphenol, attenuates lipopolysaccharide-induced oxidative stress in rat liver.
PubMed Open HTML    
Sebai H Ben-Attia M  » 
Ecotoxicol Environ Saf (2010) Show Abstract »
The polyphenol also abrogated LPS-induced liver and plasma nitric oxide (NO) elevation and attenuated endotoxemia-induced hepatic tissue injury.
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5
Silybin and the other silymarin flavonolignans from milk thistle conserve tissue glutathione, are liver-protective, and have anticancer potential.
6
The findings confirm that genistein increases the potential for hepatic and systemic exposure to hepatically generated glucuronides, which may be important for patients on conventional drugs who consume isoflavones.
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7
These results are consistent with the view that many, but not all, flavonoids inhibit the hepatic and duodenal sulphation of resveratrol, and such inhibition might improve the bioavailability of this compound.
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8
In fact, silibinin promoted an increase of ATP and RCR by, respectively, 39 and 16% and decreased oxidative stress to values observed in livers never preserved nor perfused.
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9 Full-text article
Hepatoprotective and anti-inflammatory activities of Plantago major L
PubMed Central Open HTML Open PDF     PubMed Open HTML    
Türel I Yilmaz O  » 
Indian J Pharmacol (2009) Show Abstract »
Plantago major L. (25 mg/kg) or silibinin-treated livers showed significant recovery.
10
Flavanone metabolism in healthy and tumor-bearing rats.
PubMed Open HTML    
Silberberg M Morand C  » 
Biomed Pharmacother (2006) Show Abstract »
Flavanones were analyzed in plasma, liver, kidney and urine by tandem mass spectrometry.
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