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1
From histamine to imidazolylalkyl-sulfonamides: the design of a novel series of histamine H3-receptor antagonists.
PubMed Open HTML    
Tozer MJ Watt GF  » 
Bioorg Med Chem Lett (1999) Show Abstract »
Histamine was converted to a selective histamine H3-receptor antagonist by capping the primary amine with 2-naphthalenesulfonyl chloride.
2
Effects of the H3 receptor inverse agonist thioperamide on cocaine-induced locomotion in mice: role of the histaminergic system and potential pharmacokinetic interactions.
PubMed Open HTML    
Brabant C Tirelli E  » 
Psychopharmacology (Berl) (2008) Show Abstract »
The present results indicate that histamine released by thioperamide through the blockade of H3 autoreceptors is not involved in the ability of this compound to potentiate cocaine induced-hyperactivity.
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3
Hematopoietic progenitor cells can take up histamine or release IL-3-induced histamine through a bi-directional transport system that is blocked by H3-receptor antagonists.
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4
Thus, the blockade by mepyramine of the thioperamide-induced decrease in seizure susceptibility indicates that histamine released by thioperamide from the histaminergic nerve terminals interacts with the histamine H1 receptors of postsynaptic neurons.
5
[3H]-thioperamide as a radioligand for the histamine H3 receptor in rat cerebral cortex.
PubMed Central Open HTML Open PDF     PubMed Open HTML    
Alves-Rodrigues A Timmerman H  » 
Br J Pharmacol (1996) Show Abstract »
Binding of 0.3 nM [3H]-thioperamide was completely displaced by several H3 antagonists (thioperamide, iodophenpropit, iodoproxyfan, and burimamide) and biphasic displacement curves were obtained; the Ki values for the high affinity site corresponded well with the expected values for the H3 receptor.
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6
Effect of inflammatory mediators on the electrophysiology of the human oviduct.
PubMed Open HTML    
Downing SJ Leese HJ  » 
Biol Reprod (1999) Show Abstract »
Cimetidine, (H(2) receptor antagonist), ranitidine, or thioperamide reduced the histamine effect.
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7
When used singly, both yohimbine and thioperamide facilitated HA release.
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8
Effects of selected histamine H3 receptor antagonists on tele-methylhistamine levels in rat cerebral cortex.
PubMed Open HTML    
Yates SL Hough LB  » 
Biochem Pharmacol (1999) Show Abstract »
Thus, H3 receptor antagonists may differentially affect HA release and turnover, and brain t-MH levels may not be reliable predictors of H3 agonist, partial agonist, or antagonist in vivo activity.
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9
Histamine enhances inhibitory avoidance memory consolidation through a H2 receptor-dependent mechanism.
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da Silva WC Cammarota M  » 
Neurobiol Learn Mem (2006) Show Abstract »
Conversely, the promnesic action of histamine was unaffected by the H1 receptor antagonist pyrilamine, the H3 receptor antagonist, thioperamide, and the NMDAr polyamine-binding site antagonist ifenprodil.
10
Somatostatin antibody increased basal histamine secretion and abolished the decrease in histamine and acid secretion induced by thioperamide, confirming that changes in histamine and acid secretion induced by the activation of H3 receptors reflected changes in somatostatin secretion.
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