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1
Synergy between low-dose ranitidine and antacid in decreasing gastric and oesophageal acidity and relieving meal-induced heartburn.
PubMed Open HTML    
Robinson M Gardner JD  » 
Aliment Pharmacol Ther (2001) Show Abstract »
Ranitidine significantly decreased gastric but not oesophageal acidity, whilst antacid significantly decreased oesophageal but not gastric acidity.
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2
Omeprazole, nitrendipine, famotidine and stress-induced ulcers.
PubMed Open HTML    
Inalöz SS Ulak G  » 
Acta Gastroenterol Belg (1997) Show Abstract »
Famotidine is one of the newer histamine H2-receptor antagonists and heals gastric and duodenal ulcers by reducing gastric acid output.
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3
In order to improve the preparation method for barium examination of the stomach by ranitidine and acetylcysteine use, the effect on the rat gastric mucosa caused by the administration of ranitidine and acetylcysteine was studied.
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4
Cimetidine and mucosal cell renewal in the duodenum.
PubMed Open HTML    
Smedley FH, Wastell C
Eur Surg Res (1988) Show Abstract »
Cimetidine may protect gastric and duodenal mucosa by increasing cell turnover.
5
It was found that: (i) PG12 (in a dose of 5 micrograms.kg-1) atropine (in a dose of 0.025 mg.kg-1) and cimetidine (in a dose of 2.5 micrograms.kg-1) have cytoprotective effects; (ii) the gastric fundic mucosal damage produced by intragastric administration of 0.6 M HCl appears as a result of a positive metabolic adaptation of the gastric fundic mucosa; (iii) the development of gastric cytoprotection by PG12, atropine and cimetidine give rise to very different changes in the tissue levels of ATP, ADP, AMP and cAMP.(ABSTRACT TRUNCATED AT 400 WORDS)
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6 Full-text article
Early effects of oral administration of lafutidine with mosapride compared with lafutidine alone on intragastric pH values
BioMed Central Open HTML Open PDF     PubMed Open HTML    
Iida H Nakajima A  » 
BMC Gastroenterol (2009) Show Abstract »
Because mosapride accelerates gastric emptying, Lafutidine can pass from stomach to duodenum and be absorbed quickly.
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7
[Zollinger-Ellison syndrome]
PubMed Open HTML    
Becker HD
Wien Klin Wochenschr (1984) Show Abstract »
Because of the high malignancy rate, therapeutically, a symptomatic treatment of gastric hypersecretion by H2-receptor antagonists or in cases of ineffective conservative treatment total gastrectomy is performed.
8
These results suggest that lafutidine, but not cimetidine, protects the stomach against NH2Cl, whether occurring endogenously or administered exogenously and that this action may be mediated by capsaicin-sensitive sensory neurons.
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9
1 The absorption of a single oral dose of cimetidine taken on a fasting stomach or together with a meal was studied in 28 patients before and during 12 weeks treatment with cimetidine. 2 No significant changes in bioavailability were seen during treatment measured as the area under the blood concentration curve (AUC). 3 AUC after a single dose of 400 mg cimetidine was 2.05 times the area after a 200 mg dose. 4 There was a good correlation between AUC and the dose of cimetidine given corrected for body weight (r=0.89). 5 There was no difference in bioavailability if 200 mg cimetidine was taken on a fasting stomach or together with a beef steak meal. 6.
10
The preventive effect of cimetidine on producing stress ulcer in rats.
PubMed Open HTML    
Sugimachi K Inokuchi K  » 
Jpn J Surg (1978) Show Abstract »
Cimetidine, therefore, seems to be very effective in preventing stress induced ulcers in rat when instilled in the stomach before the stress.
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