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1
Cdc25B regulates cell cycle progression and genetic stability.
2
Cdc25A regulates cell cycle progression, has oncogenic and anti-apoptotic activity, and is over-expressed in many human tumors.
3 Full-text article
Capsaicin Displays Anti-Proliferative Activity against Human Small Cell Lung Cancer in Cell Culture and Nude Mice Models via the E2F Pathway
PubMed Central Open HTML Open PDF     PubMed Open HTML    
Brown KC Dasgupta P  » 
PLoS One (2010) Show Abstract »
These free E2Fs subsequently bind to target proliferative promoters like cyclin E, thymidylate synthase (TS), cdc25A and cdc6, which regulate cell cycle progression , .
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4
Changes in gene expression induced by chemoradiation in advanced cervical carcinoma: a microarray study of RTOG C-0128.
PubMed Open HTML    
Zempolich K Gaffney DK  » 
Gynecol Oncol (2008) Show Abstract »
Genes significantly downregulated included topoisomerase II alpha, myc, H2AX, MSH2, RAD51, RAD53, PCNA, and cell cycle-regulating molecules chk1, CDK2, cyclinB1, cyclin D3, cdc2, and cdc25.
5
Changes of cell cycle-regulating genes in interferon-treated Daudi cells.
PubMed Open HTML    
Yamada H Horiguchi-Yamada J  » 
Mol Cell Biochem (1994) Show Abstract »
Both the cell cycle distribution and the expression of cell cycle-regulating genes (cdk2, cdc2, cyclins A, B, C, D3, cdc25, and wee 1) were studied by flow cytometry and by Northern blot hybridization or the reverse-transcription polymerase chain reaction, respectively.
6 Full-text article
ATP modulates PTEN subcellular localization in multiple cancer cell lines
PubMed Central Open HTML Open PDF     PubMed Open HTML    
Lobo GP Eng C  » 
Hum Mol Genet (2008) Show Abstract »
Indeed, nuclear PTEN has been shown to regulate cell cycle and to regulate MAPK activation (,).
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7
Both PTEN and survivin proteins can regulate cell cycle and apoptosis, but their biological effects are adverse.
8
We now report that hypoxic exposure of colon cancer cells decreased the protein levels of the cell cycle-controlling phosphatase Cdc25A.
9
Additionally, we and others have shown that PTEN can regulate not only the cell cycle but also cellular apoptosis.
10
Taken together, these findings indicate that PTEN may modulate cell death or the cell cycle via AKT inactivation by PTEN and gamma-IR treatment.
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